Association of peroxisome proliferator-activated receptor gamma 2 Pro-12-Ala polymorphism with endometriosis

Songuel Dogan; Fausto Machicao; Diethelm Wallwiener; Hans-Ulrich Haering; Klaus Diedrich; Daniela Hornung

doi:10.1016/j.fertnstert.2003.10.026

Association of peroxisome proliferator-activated receptor gamma 2 Pro-12-Ala polymorphism with endometriosis

Fertil Steril. 2004 May;81(5):1411-3. doi: 10.1016/j.fertnstert.2003.10.026.

Authors

Songuel Dogan, Fausto Machicao, Diethelm Wallwiener, Hans-Ulrich Haering, Klaus Diedrich, Daniela Hornung

PMID: 15136115
DOI: 10.1016/j.fertnstert.2003.10.026

Abstract

We explored the association of the PPAR-gamma2 (peroxisome proliferator-activated receptor) Pro-12-Ala polymorphism with endometriosis in a case-control study with 51 women with endometriosis stages I-IV and 55 control women without endometriosis. The 12-Pro allele of PPAR-gamma2 may have protective effects avoiding the development and progression of endometriosis.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Base Sequence
Endometriosis / genetics*
Endometriosis / therapy
Female
Humans
Middle Aged
Molecular Sequence Data
Polymorphism, Genetic*
Receptors, Cytoplasmic and Nuclear / genetics*
Transcription Factors / genetics*

Substances

Receptors, Cytoplasmic and Nuclear
Transcription Factors