Ligand efficiency: a useful metric for lead select...[Drug Discov Today. 2004]

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1: Drug Discov Today. 2004 May 15;9(10):430-1. Links

Ligand efficiency: a useful metric for lead selection.

PMID: 15109945 [PubMed - indexed for MEDLINE]

Ligand efficiency indices as guideposts for drug discovery.
Drug Discov Today. 2005 Apr 1; 10(7):464-9.

[Drug Discov Today. 2005]
ReviewLigand-based drug design methodologies in drug discovery process: an overview.
Curr Drug Discov Technol. 2006 Sep; 3(3):155-65.

[Curr Drug Discov Technol. 2006]
Benchmarking sets for molecular docking.
J Med Chem. 2006 Nov 16; 49(23):6789-801.

[J Med Chem. 2006]
ReviewMolecular modeling of hydration in drug design.
Curr Opin Drug Discov Devel. 2007 May; 10(3):275-80.

[Curr Opin Drug Discov Devel. 2007]
Molecular modelling.
Mol Biosyst. 2006 Dec; 2(12):660-81. Epub 2006 Oct 19.

[Mol Biosyst. 2006]
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A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy.
Ramsden NL, Buetow L, Dawson A, Kemp LA, Ulaganathan V, Brenk R, Klebe G, Hunter WN. J Med Chem. 2009 Apr 23; 52(8):2531-42.

[J Med Chem. 2009]
Discovery of a non-peptidic inhibitor of west nile virus NS3 protease by high-throughput docking.
Ekonomiuk D, Su XC, Ozawa K, Bodenreider C, Lim SP, Yin Z, Keller TH, Beer D, Patel V, Otting G, et al. PLoS Negl Trop Dis. 2009; 3(1):e356. Epub 2009 Jan 13.

[PLoS Negl Trop Dis. 2009]
ReviewStructure-based ligand design and the promise held for antiprotozoan drug discovery.
Hunter WN. J Biol Chem. 2009 May 1; 284(18):11749-53. Epub 2008 Dec 22.

[J Biol Chem. 2009]
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