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1: Immunol Today. 1992 Aug;13(8):306-14.Links

VDJ recombination.

Alt FW, Oltz EM, Young F, Gorman J, Taccioli G, Chen J.

The ability of lymphocyte receptor V, D and J gene segments to rearrange generates much of the receptor diversity that is the hallmark of the immune system. Naturally, the mechanisms of immunoglobulin and T-cell receptor gene recombination are of enormous interest. Here, Fred Alt and colleagues review current understanding of the process and speculate on future findings.

PMID: 1510813 [PubMed - indexed for MEDLINE]

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