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1: CNS Spectr. 2002 Sep;7(9):655-7.Links

Citalopram for social anxiety disorder: an open-label pilot study in refractory and nonrefractory patients.

Simon NM, Korbly NB, Worthington JJ, Kinrys G, Pollack MH.

Department of Psychiatry, Harvard Medical School, Boston, MA, USA. nsimon@partners.org

There is limited systematic data assessing alternate pharmacotherapy of social anxiety disorder in patients failing to tolerate or fully respond to initial treatment; no data specifically address the efficacy of citalopram in this scenario. We present a prospective open-label trial of citalopram in 10 patients with generalized social anxiety disorder, 6 of 10 of whom had not responded to or not tolerated a prior treatment intervention for the disorder. Citalopram, at a mean dose of 55 mg (SD+/-12.7 mg) was well tolerated, and patients improved significantly on all outcome measures. Results of this study suggest that citalopram may be a safe and effective treatment for generalized social anxiety disorder, including patients who have failed to tolerate or respond to a prior treatment trial.

PMID: 15097929 [PubMed]

Patient Drug Information

  • Escitalopram (Lexapro® )

    Escitalopram is used to treat depression and generalized anxiety disorder (GAD; excessive worry and tension that disrupts daily life and lasts for 6 months or longer). Escitalopram is in a class of antidepressants called...

  • Bupropion (Wellbutrin, Wellbutrin, Wellbutrin XL, ...)

    How do the newer antidepressants compare in treating depression?

  • Citalopram (Celexa® )

    Citalopram is used to treat depression. Citalopram is in a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs). It works by increasing the amount of serotonin, a natural substance in the brain...

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