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Food additives intolerance: does it present as perennial rhinitis?

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  • 1Head of the Allergy Unit, San Carlo Clinic, Paderno Dugnano (MI), Italy. r.asero@libero.it

Abstract

PURPOSE OF REVIEW:

A case report published in 2001 raised the possibility that some patients with long-lasting 'nonallergic' perennial rhinitis might in effect have food additives intolerance. The recent literature published in English was reviewed to find controlled studies able to confirm this observation.

RECENT FINDINGS:

Two double-blind, placebo-controlled studies published between August 2002 and July 2003 confirmed the above observation. The prevalence of additives intolerance among individuals with 'nonallergic' perennial rhinitis is about 5%. The pathogenic mechanisms involved remain unclear.

SUMMARY:

Intolerance to food additives may sometimes present as perennial rhinitis. Clinicians should consider this possibility before they definitively dismiss patients as 'nonallergic'.

PMID:
15090915
[PubMed - indexed for MEDLINE]
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