J Pediatr Hematol Oncol. 2004 Apr;26(4):270-1.

Severe vitamin B12 deficiency in an infant associated with a maternal deficiency and a strict vegetarian diet.

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Department of Family Medicine, Ha'Emek Medical Center, Afula, Israel.

Abstract

The authors present a case of severe megaloblastic anemia and neurologic damage due to vitamin B12 deficiency in a 6-month-old infant. The cause of the vitamin deficiency was a maternal dietary deficiency because of a strict vegetarian diet and prolonged breast-feeding. The importance of early recognition of significant maternal vitamin B12 deficiency during pregnancy and lactation in vegetarians is emphasized so that appropriate supplementation can be given and irreversible neurologic damage in the infant prevented.

PMID:: 15087959; [PubMed - indexed for MEDLINE]

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Vitamin B 12

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[Severe vitamin B12 deficiency in infants breastfed by vegans]. [Ugeskr Laeger. 2009]
[Severe vitamin B12 deficiency in infants breastfed by vegans].
Roed C, Skovby F, Lund AM. Ugeskr Laeger. 2009 Oct 19; 171(43):3099-101.
A syndrome of methylmalonic aciduria, homocystinuria, megaloblastic anemia and neurologic abnormalities in a vitamin B12-deficient breast-fed infant of a strict vegetarian. [N Engl J Med. 1978]
A syndrome of methylmalonic aciduria, homocystinuria, megaloblastic anemia and neurologic abnormalities in a vitamin B12-deficient breast-fed infant of a strict vegetarian.
Higginbottom MC, Sweetman L, Nyhan WL. N Engl J Med. 1978 Aug 17; 299(7):317-23.
Nutritional vitamin B12 deficiency in a breast-fed infant of a vegan-diet mother. [Clin Pediatr (Phila). 1986]
Nutritional vitamin B12 deficiency in a breast-fed infant of a vegan-diet mother.
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Review Nutritional vitamin B12 deficiency in infancy: three case reports and a review of the literature. [Pediatr Hematol Oncol. 1989]
Review Nutritional vitamin B12 deficiency in infancy: three case reports and a review of the literature.
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Cited by 3 PubMed Central articles

Severe megaloblastic anaemia in an infant. [BMJ Case Rep. 2011]
Severe megaloblastic anaemia in an infant.
Rodrigues V, Dias A, Brito MJ, Galvão I, Ferreira GC. BMJ Case Rep. 2011 May 16; 2011. Epub 2011 May 16.
Neuro-regression in vitamin B12 deficiency. [BMJ Case Rep. 2009]
Neuro-regression in vitamin B12 deficiency.
Agrawal S, Nathani S. BMJ Case Rep. 2009; 2009. Epub 2009 Mar 17.
Case 2: A pale infant - not a typical case of iron deficiency. [Paediatr Child Health. 2008]
Case 2: A pale infant - not a typical case of iron deficiency.
Wong MP, Wadsworth L, Wu JK, Dix D. Paediatr Child Health. 2008 Jul; 13(6):507-11.

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Severe vitamin B12 deficiency in an infant associated with a maternal deficiency and a strict vegetarian diet.
J Pediatr Hematol Oncol. 2004 Apr ;26(4):270-1.

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