A mixed methods design was used to collect data from 30 men who were currently, or had a history of, participating in anonymous public sex in college campus venues. Data were analyzed to assess the extent to which participation in these behaviors was associated with both positive and negative outcomes across the areas of physical health, mental health and social well-being. Findings indicated that cruising for sex on a college campus simultaneously presents challenges to, and supports, the health of gay and bisexual men. Recommendations for interfacing with these men by campus and community health providers are given.