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Science. 2004 Apr 9;304(5668):242-8.

Bacterial invasion: the paradigms of enteroinvasive pathogens.

Author information

  • 1Unité des Interactions Bactéries-Cellules, INSERM Unité 604, Département de Biologie Cellulaire et Infection, Institut Pasteur, 28 Rue du Docteur Roux, Paris 75015, France. pcossart@pasteur.fr

Abstract

Invasive bacteria actively induce their own uptake by phagocytosis in normally nonphagocytic cells and then either establish a protected niche within which they survive and replicate, or disseminate from cell to cell by means of an actin-based motility process. The mechanisms underlying bacterial entry, phagosome maturation, and dissemination reveal common strategies as well as unique tactics evolved by individual species to establish infection.

PMID:
15073367
[PubMed - indexed for MEDLINE]
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