My NCBISign In

Display Settings:

Format

Send to:

Choose Destination
    Pediatr Nephrol. 2004 Jul;19(7):780-4. Epub 2004 Apr 8.

    Comparison of two formulae for estimation of glomerular filtration rate in children.

    Hellerstein S, Berenbom M, DiMaggio S, Erwin P, Simon SD, Wilson N.

    Source

    Section of Nephrology, The Children's Mercy Hospital, The University of Missouri School of Medicine at Kansas City, Kansas City, Missouri 64108, USA. shellers@ cmh.edu

    Abstract

    Glomerular filtration rate (GFR) was measured in 216 studies in 151 children using the cimetidine protocol. This was compared with the GFR calculated using Léger's pharmacokinetic equation and with that calculated using k*L/[Cr](s )(constant x length in centimeters divided by serum creatinine concentration). The GFR calculated using the equation GFR=k*L/[Cr](s) yielded a closer approximation to the measured GFR than that using Léger's pharmacokinetic equation. Currently there is focus on screening children for decreased GFR to identify those with asymptomatic chronic kidney disease at a time when intervention may delay progression to chronic renal failure. This study showed close approximation of the calculated GFR with the measured GFR using the equation GFR=k*L/[Cr](s), when the values for k were determined in the laboratory in which creatinine was measured.

    PMID:
    15071771
    [PubMed - indexed for MEDLINE]

    Publication Types, MeSH Terms, Substances

    Publication Types

    MeSH Terms

    Substances

    LinkOut - more resources

    Full Text Sources

    Medical

    Molecular Biology Databases

      Supplemental Content

      Icon for Springer

      Save items

      loading

      Related citations in PubMed

      See reviews... See all...

      Cited by 1 PubMed Central article

      • New equations to estimate GFR in children with CKD. [J Am Soc Nephrol. 2009]
        New equations to estimate GFR in children with CKD.
        Schwartz GJ, Muñoz A, Schneider MF, Mak RH, Kaskel F, Warady BA, Furth SL. J Am Soc Nephrol. 2009 Mar; 20(3):629-37. Epub 2009 Jan 21.

      Related information

      • Related Citations
        Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
      • Compound (MeSH Keyword)
        PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
      • Substance (MeSH Keyword)
        PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
      • Cited in PMC
        Full-text articles in the PubMed Central Database that cite the current articles.

      Recent activity

      Clear Turn Off Turn On

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...
      You are here: NCBI > Literature > PubMed
      Write to the Help Desk