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J Am Vet Med Assoc. 2004 Mar 15;224(6):892-4.

Thyroid function and pregnancy status in broodmares.

Author information

  • 1Section of Reproduction, Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA 19348, USA.

Abstract

OBJECTIVE:

To determine whether thyroid function was associated with pregnancy status in broodmares.

DESIGN:

Prospective study.

ANIMALS:

79 Thoroughbred and Standardbred broodmares between 2 and 22 years old.

PROCEDURE:

Serum triiodothyronine (T3) concentration was measured before and 2 hours after i.v. administration of thyrotropin releasing hormone (TRH), and serum thyroxine (T4) concentration was measured before and 4 hours after TRH administration. Pregnancy status was monitored by means of transrectal ultrasonography beginning 16 days after ovulation.

RESULTS:

Baseline T3 and T4 concentrations varied widely. In all mares, serumT3 concentration increased in response to TRH administration. Serum T4 concentration increased in response toTRH administration in all but 2 mares. Pregnancy rate was 76%. Baseline and stimulated serum T3 and T4 concentrations were not significantly different between mares that became pregnant and those that did not.

CONCLUSIONS AND CLINICAL RELEVANCE:

Results suggest that decreased thyroid function is uncommon in mares and poor thyroid function is not a common cause of infertility. Thus, the practice of indiscriminately treating broodmares with thyroid hormone to enhance fertility appears questionable at this time.

PMID:
15070060
[PubMed - indexed for MEDLINE]
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