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J Pediatr. 2004 Apr;144(4):541-4.

Crohn's-associated chronic recurrent multifocal osteomyelitis responsive to infliximab.

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  • 1Inflammatory Bowel Disease Program, Section of Gastroenterology, The Children's Mercy Hospital and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA.


We report a case of chronic recurrent clavicular osteomyelitis in association with Crohn disease. Steroid therapy resulted in partial remission; however, intractable shoulder pain and an enlarging clavicular mass subsequently recurred. Infliximab therapy resulted in significant improvement in the degree of bone pain and resolution of the large sclerotic clavicular lesion.

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