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[Study status of collagen-based biomaterials in drug release and tissue engineering].

[Article in Chinese]

Author information

  • 1Derma Tissue Engineering Laboratory, Sichuan University, Chengdu, Sichuan, P. R. China 610065. biwang123@163.com

Abstract

OBJECTIVE:

To introduce the development of the collagen materials in drug release and tissue engineering.

METHODS:

Literature review and complex analysis were adopted.

RESULTS:

In recent years, some good progress has been made in the studies of collagen, and study on collagen-based materials has become an investigative hotspot especially in tissue engineering. Some new collagen-based drug delivery and engineered materials have come into clinically-demonstrated moment, which will promote their clinical applications in tissue repairs.

CONCLUSION:

Collagen has been considered a good potential material in drug release, especially in the tissue-engineering field. To give collagen new characters we should pay more attention to grafting with different function branches through chemistry technique in the future work, except moderate cross-linking treatment or commingling with other nature or synthesized macromolecules.

PMID:
15065409
[PubMed - indexed for MEDLINE]
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