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Dermatology. 2004;208(2):142-4.

Familial Lassueur-Graham-Little-Piccardi syndrome.

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  • 1Department of Endocrinologic and Metabolic Diseases, University of Genoa, Genoa, Italy.


Lassueur-Graham-Little-Piccardi syndrome (LGLPS) is a rare lichenoid dermatosis characterized by progressive cicatricial alopecia of the scalp, loss of pubic and axillary hairs and keratosis pilaris. The syndrome is considered a form of follicular lichen planus (LP). Although the familial occurrence of LP is a well-described phenomenon, no familial case of LGLPS has ever been reported. We describe the occurrence of LGLPS in a mother and her daughter. HLA typing revealed HLA-DR1 in both patients. Topical tacrolimus was of partial benefit in the daughter.

Copyright 2004 S. Karger AG, Basel

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