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Center for Infectious Disease and Vaccine Research, S5-326 University of Massachusetts Medical School, Worcester, 01655, USA.
Puumala virus, causative agent of a mild form of hemorrhagic fever with renal syndrome, also known as nephropathia epidemica, induces long-lasting humoral and cellular immunity in patients. The virus itself is not cytopathic, and the immune responses to the virus may be involved in teh pathogenesis of the disease.
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