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1: Oncology (Williston Park). 2002 Mar;16(3):309-15; discussion 315, 318, 323-4.Links

Current approaches to the treatment of well-differentiated thyroid cancer.

Angelos P.

Department of Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA.

The management of well-differentiated thyroid cancer requires a multidisciplinary approach. The majority of patients are diagnosed only after a nodule is palpable. A cytologic evaluation can readily diagnose a papillary thyroid carcinoma but a follicular carcinoma requires determination of capsular or vascular invasion. Surgical considerations in well-differentiated thyroid cancer are frequently complicated by the need to operate on patients with indeterminate nodules. Also, the extent of surgery remains controversial. A total or near-total thyroidectomy has several advantages: (1) radioactive iodine can be used to ablate any residual thyroid tissue or cancer cells; (2) thyroglobulin levels can be used to follow a patient for recurrence; (3) the risk of leaving a focus of carcinoma in the remaining lobe is eliminated.

PMID: 15046390 [PubMed - indexed for MEDLINE]

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