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Nat Rev Mol Cell Biol. 2004 Feb;5(2):100-9.

Traffic jams affect plant development and signal transduction.

Author information

  • 1Center for Plant Cell Biology, University of California, Riverside, California 92521, USA. msurpin@pop.ucr.edu

Erratum in

  • Nat Rev Mol Cell Biol. 2004 Apr;5(4):329.


Analysis of the Arabidopsis thaliana endomembrane system has shown that plant cell viability depends on a properly functioning vacuole and intact vesicular trafficking. The endomembrane system is also essential for various aspects of plant development and signal transduction. In this review, we discuss examples of these newly discovered roles for the endomembrane system in plants, and new experimental approaches and technologies that are based on high-throughput screens, which combine chemical genetics and automated confocal microscopy.

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