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    Bioorg Khim. 2004 Jan-Feb;30(1):80-3.

    [Synthesis and properties of fluorescently-labelled triglyceride, derivative of the antineoplastic agent sarcolysin].

    [Article in Russian]
    Boldyrev IA, Grechishnikova IV, Pavlova IuB, Molotkovskiĭ IuG.

    Source

    Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, GSP Moscow, 117997 Russia.

    Abstract

    A new fluorescent probe, a 3-perylenoyl derivative of the lipophilized antitumor drug merphalan (sarcolysine), was synthesized. The probe is suitable for studying intracellular traffic and metabolism of merphalan and its derivatives. The perylenoyl fluorescence is partially quenched by the merphalan chromophore, which broadens the probe potentialities. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2004, vol. 30, no. 1; see also http://www.maik.ru.

    PMID:
    15040307
    [PubMed - indexed for MEDLINE]

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