Am J Epidemiol. 2004 Apr 1;159(7):702-6.

A modified poisson regression approach to prospective studies with binary data.

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Robarts Clinical Trials, Robarts Research Institute, London, Ontario, Canada. gzou@robarts.ca

Abstract

Relative risk is usually the parameter of interest in epidemiologic and medical studies. In this paper, the author proposes a modified Poisson regression approach (i.e., Poisson regression with a robust error variance) to estimate this effect measure directly. A simple 2-by-2 table is used to justify the validity of this approach. Results from a limited simulation study indicate that this approach is very reliable even with total sample sizes as small as 100. The method is illustrated with two data sets.

PMID:: 15033648; [PubMed - indexed for MEDLINE]

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