Curr Biol. 2004 Mar 9;14(5):R198-200.

Plant RNAi: How a viral silencing suppressor inactivates siRNA.

Source

Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA. pnillip.zamore@umassmed.edu

Abstract

The three-dimensional structure of an siRNA bound to the tombusvirus p19 protein--a suppressor of gene silencing--provides a first glimpse into how plant viruses can defeat their host's anti-viral RNAi defenses.

PMID:: 15028237; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Supplemental Content

Save items

Related citations in PubMed

Inhibition of 3' modification of small RNAs in virus-infected plants require spatial and temporal co-expression of small RNAs and viral silencing-suppressor proteins. [Nucleic Acids Res. 2008]
Inhibition of 3' modification of small RNAs in virus-infected plants require spatial and temporal co-expression of small RNAs and viral silencing-suppressor proteins.
Lózsa R, Csorba T, Lakatos L, Burgyán J. Nucleic Acids Res. 2008 Jul; 36(12):4099-107. Epub 2008 Jun 6.
Recognition of small interfering RNA by a viral suppressor of RNA silencing. [Nature. 2003]
Recognition of small interfering RNA by a viral suppressor of RNA silencing.
Ye K, Malinina L, Patel DJ. Nature. 2003 Dec 18; 426(6968):874-8. Epub 2003 Dec 3.
Biological relevance of a stable biochemical interaction between the tombusvirus-encoded P19 and short interfering RNAs. [J Virol. 2006]
Biological relevance of a stable biochemical interaction between the tombusvirus-encoded P19 and short interfering RNAs.
Omarov R, Sparks K, Smith L, Zindovic J, Scholthof HB. J Virol. 2006 Mar; 80(6):3000-8.
Review Effects and side-effects of viral RNA silencing suppressors on short RNAs. [Trends Plant Sci. 2004]
Review Effects and side-effects of viral RNA silencing suppressors on short RNAs.
Silhavy D, Burgyán J. Trends Plant Sci. 2004 Feb; 9(2):76-83.
Review Silencing suppressors: viral weapons for countering host cell defenses. [Protein Cell. 2011]
Review Silencing suppressors: viral weapons for countering host cell defenses.
Song L, Gao S, Jiang W, Chen S, Liu Y, Zhou L, Huang W. Protein Cell. 2011 Apr; 2(4):273-81. Epub 2011 Apr 27.

See reviews... See all...

Cited by 12 PubMed Central articles

Ebolavirus proteins suppress the effects of small interfering RNA by direct interaction with the mammalian RNA interference pathway. [J Virol. 2011]
Ebolavirus proteins suppress the effects of small interfering RNA by direct interaction with the mammalian RNA interference pathway.
Fabozzi G, Nabel CS, Dolan MA, Sullivan NJ. J Virol. 2011 Mar; 85(6):2512-23. Epub 2011 Jan 12.
Viral protein inhibits RISC activity by argonaute binding through conserved WG/GW motifs. [PLoS Pathog. 2010]
Viral protein inhibits RISC activity by argonaute binding through conserved WG/GW motifs.
Giner A, Lakatos L, García-Chapa M, López-Moya JJ, Burgyán J. PLoS Pathog. 2010 Jul 15; 6(7):e1000996. Epub 2010 Jul 15.
Virus infection elevates transcriptional activity of miR164a promoter in plants. [BMC Plant Biol. 2009]
Virus infection elevates transcriptional activity of miR164a promoter in plants.
Bazzini AA, Almasia NI, Manacorda CA, Mongelli VC, Conti G, Maroniche GA, Rodriguez MC, Distéfano AJ, Hopp HE, del Vas M, et al. BMC Plant Biol. 2009 Dec 30; 9:152. Epub 2009 Dec 30.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Plant RNAi: How a viral silencing suppressor inactivates siRNA.
Plant RNAi: How a viral silencing suppressor inactivates siRNA.
Curr Biol. 2004 Mar 9 ;14(5):R198-200.

PubMed
Evidence for a Hox14 paralog group in vertebrates.
Evidence for a Hox14 paralog group in vertebrates.
Curr Biol. 2004 Mar 9 ;14(5):R183-4.

PubMed
Mechanical characterization of biocompatible microspheres and microcapsules by d...
Mechanical characterization of biocompatible microspheres and microcapsules by direct compression.
Artif Cells Blood Substit Immobil Biotechnol. 2004 Feb ;32(1):25-40.

PubMed
Urologists and circumcision of newborns.
Urologists and circumcision of newborns.
Urology. 1992 Aug ;40(2):99-101.

PubMed
Use of desferoxamine and S-adenosylmethionine to treat hemochromatosis in a red ...
Use of desferoxamine and S-adenosylmethionine to treat hemochromatosis in a red ruffed lemur (Varecia variegata ruber).
Comp Med. 2004 Feb ;54(1):100-3.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: