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Curr Biol. 2004 Mar 9;14(5):R198-200.

Plant RNAi: How a viral silencing suppressor inactivates siRNA.

Author information

  • Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA. pnillip.zamore@umassmed.edu

Abstract

The three-dimensional structure of an siRNA bound to the tombusvirus p19 protein--a suppressor of gene silencing--provides a first glimpse into how plant viruses can defeat their host's anti-viral RNAi defenses.

PMID:
15028237
[PubMed - indexed for MEDLINE]
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