J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Apr 15;803(1):17-26.

Differential polypeptide display: the search for the elusive target.

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Mosaiques Diagnostics and Therapeutics AG, Hannover, Germany.

Abstract

Proteomics, as a tool to identify proteins in biological samples, is gaining rapidly importance in the postgenomic era. Here we discuss the current and potential role of different techniques in the field of proteomics such as two-dimensional gel electrophoresis off-line coupled to MALDI-MS (2D-PAGE-MALDI-MS), high performance liquid chromatography mass spectrometry (HPLC-MS), surface enhanced laser desorption/ionization mass spectrometry (SELDI-MS) and a newly developed technique, capillary electrophoresis mass spectrometry (CE-MS). The developments of the last years are presented discussed.

PMID:: 15025995; [PubMed - indexed for MEDLINE]

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Peptides

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Differential polypeptide display: the search for the elusive target.
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J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Apr 15 ;803(1):17-26.

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