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Neuroimaging Clin N Am. 2003 Nov;13(4):781-9, ix.

Imaging the pathology of Alzheimer's disease: amyloid-imaging with positron emission tomography.

Author information

  • 1Laboratory of Molecular Neuropharmacology, Department of Psychiatry, University of Pittsburgh School of Medicine, 705 Parran Hall, Pittsburgh, PA 15213, USA. klunkwe@msx.upmc.edu

Abstract

The steep rise in the incidence of Alzheimer's disease (AD) has further added to the considerable public health burden caused by aging of the United States population. Among the most characteristic pathologic hallmarks of AD are neuritic plaques and neurofibrillary tangles. The capability to use positron emission tomography and selective markers for amyloid protein deposition promises to substantially alter the way we diagnosis and manage patients who have AD.

PMID:
15024961
[PubMed - indexed for MEDLINE]
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