Am J Dermatopathol. 2004 Apr;26(2):141-55.

Cutaneous and subcutaneous fibrohistiocytic tumors of intermediate malignancy: an update.

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Department of Pathology, Indiana University, Indianapolis, IN, USA.

Abstract

The fibrohistiocytic tumors of intermediate malignancy are uncommon mesenchymal tumors, which typically occur in the skin and subcutis and which may pose significant problems for the dermatopathologist. This article reviews the clinical, histopathologic, and genetic features of dermatofibrosarcoma protuberans, giant cell fibroblastoma, angiomatoid (malignant) fibrous histiocytoma, plexiform fibrous histiocytoma, and soft tissue giant cell tumor (of low malignant potential). The differential diagnosis of these tumors with a variety of benign and fully malignant cutaneous soft tissue neoplasms is discussed.

PMID:: 15024197; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

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Review

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Substances

DNA, Neoplasm

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Skin Cancer - MedlinePlus Health Information

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Cited by 2 PubMed Central articles

Review The impact of advances in molecular genetic pathology on the classification, diagnosis and treatment of selected soft tissue tumors of the head and neck. [Head Neck Pathol. 2010]
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Review Subcutaneous benign fibrous histiocytoma of the cheek. Case report and review of the literature. [Acta Otorhinolaryngol Ital. 2007]
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