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1: Phytother Res. 2004 Feb;18(2):184-6.Click here to read Links

Pseudoguaianolide sesquiterpene lactones with high activities against the human malaria parasite Plasmodium falciparum.

François G, Passreiter CM.

Prince Leopold Institute of Tropical Medicine, Antwerpen, Belgium.

Four sesquiterpene lactones of the pseudo-guaianolide type (helenalin, dihydrohelenalin and their acetates), have shown activities against asexual blood forms of Plasmodium falciparum in vitro. Their IC(50) values were situated in the range of 0.23 to 7.41 micro M. The activity found for helenalin was high, even compared to the activity found for artemisinin. Copyright 2004 John Wiley & Sons, Ltd.

PMID: 15022176 [PubMed - indexed for MEDLINE]