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Genetics. 2004 Jan;166(1):631-5.

One-hybrid screens at the Saccharomyces cerevisiae HMR locus identify novel transcriptional silencing factors.

Author information

  • 1Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York 11794, USA.

Abstract

In Saccharomyces cerevisiae, genes located at the telomeres and the HM loci are subject to transcriptional silencing. Here, we report results of screening a Gal4 DNA-binding domain hybrid library for proteins that cause silencing when targeted to a silencer-defective HMR locus.

PMID:
15020450
[PubMed - indexed for MEDLINE]
PMCID:
PMC1470702
Free PMC Article
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