Massive nasal bleeding and hemodynamic instability associated with clopidogrel

Pharm World Sci. 2004 Feb;26(1):6-7. doi: 10.1023/b:phar.0000013480.17165.6d.

Abstract

A 58-year-old woman was brought to our emergency department with massive nasal bleeding and hemodynamic instability. The patient had been on clopidogrel treatment (75 mg/day) for 2 years, which was started after an episode of transitory ischemic attack. Blood pressure normalized following the administration of intravenous fluids, and the bleeding stopped after nasal tamponade and desmopressin therapy.

Publication types

  • Case Reports

MeSH terms

  • Clopidogrel
  • Deamino Arginine Vasopressin / therapeutic use
  • Epistaxis / chemically induced*
  • Epistaxis / drug therapy
  • Epistaxis / physiopathology
  • Female
  • Hemodynamics
  • Hemostatics / therapeutic use
  • Humans
  • Ischemic Attack, Transient / drug therapy
  • Middle Aged
  • Platelet Aggregation Inhibitors / adverse effects*
  • Ticlopidine / adverse effects*
  • Ticlopidine / analogs & derivatives*

Substances

  • Hemostatics
  • Platelet Aggregation Inhibitors
  • Clopidogrel
  • Deamino Arginine Vasopressin
  • Ticlopidine