Format

Send to

Choose Destination
See comment in PubMed Commons below
Am J Perinatol. 2004 Jan;21(1):35-40.

Cord blood lipids concentrations and their relation to body size at birth: possible link between intrauterine life and adult diseases.

Author information

  • 1Department of Obstetrics and Gynecology, Western Galilee Hospital, PO Box 21, Nahariya 22100, Israel.

Abstract

Umbilical plasma levels of lipoproteins-cholesterol were measured in 480 normal newborns delivered by spontaneous vaginal delivery at 39 to 40 weeks of gestation. Plasma concentrations of lipids were related to fetal weight, abdominal and head circumference, and ponderal index at birth. Plasma concentration of low-density lipoprotein cholesterol (LDL-C) correlated negatively with abdominal circumference (AC), birth weight, and head circumference of newborns (p < 0.021, p < 0.023, p < 0.044, respectively). The baby with the smallest AC had the highest plasma concentration of LDL-C (p < 0.015). In the 165 neonates with ponderal index < 10th percentile, LDL-C was substantially elevated (p < 0.018). These findings suggest that disproportionate size at birth is associated with altered lipid metabolism. These abnormalities, if they persist, might lead to metabolic diseases in adulthood.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Georg Thieme Verlag Stuttgart, New York
    Loading ...
    Write to the Help Desk