Xenopus laevis sperm proteins, previously identified as surface proteins with egg coat binding capability, are indeed histone H4, histone H3, and sperm specific protein SP2

J Exp Zool. 1992 Aug 15;263(2):210-4. doi: 10.1002/jez.1402630211.

Abstract

Recently, four Xenopus sperm proteins thought to be involved in binding to the egg envelope were identified (Lindsay and Hedrick, J. Exp. Zool., 245:286-293, '88). We have studied the three more abundant ones of apparent molecular weight of 14, 19, and 25 kd in SDS-PAGE. We have shown that these proteins are indeed nuclear basic proteins: the 14 kd is the histone H4, the 19 kd is the histone H3, and the 25 kd is the sperm-specific protein SP2.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Histones / analysis*
  • Male
  • Membrane Proteins / analysis*
  • Molecular Sequence Data
  • Molecular Weight
  • Spermatozoa / chemistry*
  • Xenopus laevis

Substances

  • Histones
  • Membrane Proteins