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Neurology. 2004 Mar 9;62(5):806-8.

MRI criteria for multiple sclerosis: Evaluation in a pediatric cohort.

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  • 1Division of Neurology, Department of Diagnostic Imaging, The Hospital for Sick Children and University of Toronto, Ontario, Canada.


This study assessed the validity of established MRI criteria for multiple sclerosis (MS) in a cohort of 20 children with clinically definite MS. The authors found that many pediatric MS patients did not meet the MRI criteria established for adult-onset MS, particularly the McDonald MRI criteria for dissemination in space. The authors thus suggest that MRI criteria for adult MS be applied cautiously to pediatric MS patients.

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