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Identifying transcriptional targets.
Wellcome Trust/Cancer Research UK Gurdon Institute and Department of Zoology, University of Cambridge, Cambridge CB2 1QR, UK.
Identifying the targets of transcription factors is important for understanding cellular processes. We review how targets have previously been isolated and outline new technologies that are being developed to identify novel direct targets, including chromatin immunoprecipitation combined with microarray screening and bioinformatic approaches.
PMID: 15005803 [PubMed - indexed for MEDLINE]
PMCID: PMC395755
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Cited by 5 PubMed Central articles
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An Algorithm for Identifying Novel Targets of Transcription Factor Families: Application to Hypoxia-inducible Factor 1 Targets.
Jiang Y, Cukic B, Adjeroh DA, Skinner HD, Lin J, Shen QJ, Jiang BH.
Cancer Inform. 2009; 7:75-89. Epub 2009 Mar 4.
[Cancer Inform. 2009]
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Fine-tuning enhancer models to predict transcriptional targets across multiple genomes.
Aerts S, van Helden J, Sand O, Hassan BA.
PLoS One. 2007 Nov 7; 2(11):e1115. Epub 2007 Nov 7.
[PLoS One. 2007]
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ReviewMapping the genome landscape using tiling array technology.
Yazaki J, Gregory BD, Ecker JR.
Curr Opin Plant Biol. 2007 Oct; 10(5):534-42. Epub 2007 Aug 20.
[Curr Opin Plant Biol. 2007]
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