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Ann N Y Acad Sci. 2003 Dec;1008:281-4.

Sex differences and hormonal effects in a model of preterm infant brain injury.

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  • 1Department of Physiology, University of Maryland-Baltimore, Baltimore, MD 21201, USA.


Premature infants are at an exceptionally high risk for brain injury, with damage resulting in permanent behavioral deficits. A contributing factor to the severity of brain injury is gender, with males more sensitive to insult than females. The role of gender and early hormonal environment in addressed in our novel model of prenatal brain damage.

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