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Curr Top Cell Regul. 1992;33:15-30.

Association of glycolytic enzymes with the cytoskeleton.

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  • 1Department of Biochemistry and Molecular Biology, University of North Dakota School of Medicine, Grand Forks 58202.


The diverse physical associations of the glycolytic enzymes with structural components of the cell suggest that the glycolytic enzymes are not entirely soluble in the cell. The relatively low affinities of the associations are likely responsible for the apparently transient interactions. The binding phenomenon is suggested to regulate metabolism through changes in enzymatic activity and facilitates localized enrichment of the enzymes.

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