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Ann Nutr Metab. 2004;48(2):95-102. Epub 2004 Feb 25.

Effects of Western, Vegetarian, and Japanese dietary fat model diets with or without green tea extract on the plasma lipids and glucose, and liver lipids in mice. A long-term feeding experiment.

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  • 1National Food Research Institute, Kannondai, Tsukuba, Ibaraki, Japan.



The purpose of this study was to investigate the long-term effects of three model diets containing different fats, with or without a small amount of green tea extract (GTE), on plasma lipids and glucose, and liver lipids in mice.


Male mice (2 months old) fed 10% fat diets with Western (W), Vegetarian (V), and Japanese (J) fat compositions with or without 0.03% GTE for 7 months.


The concentrations of plasma and liver total cholesterol in animals fed the W diet were not significantly different from those fed the J diet. Plasma triacylglycerol (TG) concentrations were significantly different from one another in the following order: V > J > W diet groups. GTE supplementation significantly reduced plasma and liver TG content only in V diet group. Plasma glucose (Glu) concentrations were in the following order: W > V > J diet groups, and the GTE supplementation reduced the concentration of Glu in each diet group. The ratios of plasma n-6 to n-3 fatty acids were in the following order: V > W > J diet groups, regardless of GTE supplementation.


These findings show the possibility that Japanese eating habits combined with drinking green tea might be a factor in preventing the onset of non-insulin-dependent diabetes mellitus.

Copyright 2004 S. Karger AG, Basel

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