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Haemophilia. 2004 Mar;10 Suppl 1:58-62.

Setting research priorities to improve cost-effectiveness estimations of primary prophylaxis with clotting factor for people with severe haemophilia.

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  • 1Health Economics Research Group, Brunel University, Uxbridge, UK. Alec.Miners@nice.nhs.uk

Abstract

Primary prophylaxis with clotting factor is the clinical treatment of choice for people with severe haemophilia, as evidence suggests it can prevent the onset and progression of joint- and muscle-related problems caused by bleeding episodes. However, the major limitation of this approach is that it requires considerably more clotting factor compared with treating on-demand. Thus, there is a need to establish its cost-effectiveness. The aim of this paper is to review the published evidence on the cost-effectiveness of prophylaxis and to highlight areas for future research that would decrease the uncertainty around these findings.

PMID:
14987250
[PubMed - indexed for MEDLINE]
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