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J Child Adolesc Psychopharmacol. 2003 Winter;13(4):463-70.

A preliminary study of the Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children mania rating scale for children and adolescents.

Author information

  • 1Division of Child Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA. axelsonda@msx.upmc.edu

Abstract

OBJECTIVE:

To construct a mania rating scale designed for children and adolescents.

METHODS:

Fourteen questions from the Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present Episode (K-SADS-P) 1986 version plus a new item assessing mood lability were used to construct a clinician-rated mania rating scale (K-SADS-MRS). Interrater reliability was determined prospectively with 22 patients from a bipolar outpatient clinic. Sensitivity to treatment effects was determined in a separate cohort of 23 patients.

RESULTS:

Internal consistency (Cronbach's alpha = 0.94) and interrater reliability (intraclass correlation coefficient = 0.97 between two raters) were high. Convergent validity with the Clinical Global Impressions-Severity scale (bipolar version) was good (r(s)= 0.91, p < 0.001). Treatment responders had significantly greater reduction in K-SADS-MRS scores than nonresponders (-15.6 +/- 8.7 vs. 0.3 +/- 8.8), t(21) = 4.2, p < 0.001. The K-SADS-MRS scores differentiated bipolar patients who had clinically significant manic symptoms from those who did not, with a sensitivity of 87% and a specificity of 81%.

CONCLUSION:

The K-SADS-MRS shows promise as a rating scale for measuring manic symptom severity in pediatric bipolar patients.

PMID:
14977459
[PubMed - indexed for MEDLINE]
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