Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Rheumatology (Oxford). 2004 May;43(5):583-6. Epub 2004 Feb 17.

Factors influencing the beliefs of patients with rheumatoid arthritis regarding disease-modifying medication.

Author information

  • 1Lancashire School of Health and Postgraduate Medicine, University of Central Lancashire, Preston, UK. lgoodacre@uclan.ac.uk

Abstract

OBJECTIVE:

To investigate factors influencing the beliefs of patients with rheumatoid arthritis (RA) regarding disease-modifying medication.

METHOD:

Twenty-nine patients with RA either starting a disease-modifying anti-rheumatic drug (DMARD) for the first time or changing DMARD were recruited. Semi-structured interviews, activity diaries and focus groups were conducted over 9 months. A coding framework was developed and data analysed using the constant comparative method to identify key themes.

RESULTS:

DMARDs were perceived as central to the management of RA but strong concerns were expressed about potential long-term effects. Beliefs about DMARDs were informed by material from a wide range of sources. Judgements of efficacy were influenced by symptom relief, occurrence of side-effects and perception of alternative treatment options. Perception, reporting and tolerance of side-effects differed widely between individuals. The emotional impact of starting and being withdrawn from medication appeared stronger in people with more experience of DMARD use.

CONCLUSIONS:

Patients have complex and evolving belief systems relating to DMARDs. Understanding these systems will facilitate the provision of appropriate information and effective support not only in decision-making about treatment but also in relation to discontinuing treatment.

Comment in

PMID:
14970399
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk