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Bioinformatics. 2004 Jul 10;20(10):1646-8. Epub 2004 Feb 12.

OBIYagns: a grid-based biochemical simulator with a parameter estimator.

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  • 1Bioinformatics Group, RIKEN Genomic Sciences Center, 1-7-22 Suehirocho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.


OBIYagns (yet another gene network simulator) is a biochemical system simulator that comprises a multiple-user Web-based graphical interface, an ordinary differential equation solver and a parameter estimators distributed over an open bioinformatics grid (OBIGrid). This grid-based biochemical simulation system can achieve high performance and provide a secure simulation environment for estimating kinetic parameters in an acceptable time period. OBIYagns can be applied to larger system biology-oriented simulation projects.


OBIYagns example models, methods and user guide are available at


Please refer to Bioinformatics online.

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