Semin Surg Oncol. 1992 May-Jun;8(3):129-35.

The pathologist's examination of the "lumpectomy"--the pathologists' view of surgical margins.

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Department of Pathology, Baptist Hospital, Miami, FL 33176-2197.

Abstract

Despite the widespread conservative management of breast cancer, the pathologists' examination of these specimens is far from uniform. Pathologists sample margins differently, and even disagree on what constitutes a positive margin. This variability in the pathologic examination of the lumpectomy creates tremendous problems in analyzing the existing literature on the importance of positive margins. Herein is a discussion of the available data on the significance of margin assessment. We furthermore suggest a practical approach to examining margins with an emphasis on a functional orientation of the specimen with respect to the nipple. Only by adopting a uniform system of margin assessment can we begin to critically evaluate the importance of positive margins in segmental resections of the breast.

PMID:: 1496222; [PubMed - indexed for MEDLINE]

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