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Dev Cell. 2004 Feb;6(2):167-81.

Early steps in the development of the forebrain.

Author information

  • 1Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom. s.wilson@ucl.ac.uk

Abstract

The tremendous complexity of the adult forebrain makes it a challenging task to elucidate how this structure forms during embryonic development. Nevertheless, we are beginning to understand how a simple epithelial sheet of ectoderm gives rise to the labyrinthine network of cells that constitutes the functional forebrain. Here, we discuss early events in forebrain development--those that lead to the establishment of the anterior neural plate and the regional subdivision of this territory into the different domains of the prospective forebrain.

PMID:
14960272
[PubMed - indexed for MEDLINE]
PMCID:
PMC2789258
Free PMC Article

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