Abstract
Two groups of chicks were fed, until they were 3 weeks old, diets supplemented with either DL-methionine (MET) or DL-2-hydroxy-4-methylthiobutanoic acid (HMB). Oxidation to CO2 and uric catabolism of intraperitoneally injected L-[1-14C]MET and DL-[1-14C]HMB were studied comparatively for 8 h. HMB supplementation spares available MET from both oxidative and uric catabolism.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Carbon Radioisotopes
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Chickens / metabolism*
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Diet*
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Kinetics
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Methionine / administration & dosage
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Methionine / analogs & derivatives*
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Methionine / metabolism*
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Methionine / pharmacokinetics
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Methionine / pharmacology
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Uric Acid / metabolism
Substances
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Carbon Radioisotopes
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Uric Acid
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alpha-hydroxy-gamma-methylmercaptobutyric acid
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Methionine