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J Am Vet Med Assoc. 1992 Dec 15;201(12):1894-6.

Malignant anterior uveal melanoma with diffuse metastasis in a dog.

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  • 1Department of Pathology, Speyer Hospital and Caspary Research Institute, New York, NY 10021.


Enucleation was performed in 10-year-old sexually intact female mixed-breed German Shepherd Dog. Histologic examination revealed that the dog had an uveal amelanotic melanoma of the eye. The tumor consisted of anaplastic cells with a high mitotic index, indicating malignancy. On examination 3 months after enucleation, the dog had difficulty breathing and nasal discharge. Radiography revealed pulmonary metastasis. The dog was euthanatized. Necropsy revealed diffuse metastasis involving various organs.

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