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Genomics. 1992 Dec;14(4):1104-6.

Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR.

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  • 1Laboratory of Molecular Neurobiology, National Institute on Drug Abuse, Baltimore, MD 21224.

Abstract

The human dopamine transporter (DAT1) gene is localized to chromosome 5p15.3 by in situ hybridization and PCR amplification of rodent somatic cell hybrid DNA. Analysis of a 40-bp repeat in the 3' untranslated region of the message revealed variable numbers of the repeat ranging from 3 to 11 copies. These results will aid in the investigation of a role for this gene in genetic disorders of the dopaminergic system in humans.

PMID:
1478653
[PubMed - indexed for MEDLINE]
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