Genet Anal Tech Appl. 1992 Jun;9(3):73-9.

PCR-SSCP: a method for detection of mutations.

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Oncogene Division, National Cancer Center Research Institute, Tokyo, Japan.

Abstract

PCR-SSCP (polymerase chain reaction-single-strand conformation polymorphism) analysis is one of the simplest and perhaps one of the most sensitive methods for detection of mutations based on PCR technology. The principles of PCR-SSCP, guidelines for experiments, and applications of this technique in various fields are reviewed.

PMID:: 1476794; [PubMed - indexed for MEDLINE]

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PCR-SSCP: a method for detection of mutations.

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