J Bacteriol. 2004 Feb;186(4):1197-9.

PriA is essential for viability of the Escherichia coli topoisomerase IV parE10(Ts) mutant.

Grompone G, Bidnenko V, Ehrlich SD, Michel B.

Source

Laboratoire de Génétique Microbienne, Institut National de la Recherche Agronomique, 78352 Jouy en Josas, France.

Abstract

The parE10(Ts) mutation, which renders Escherichia coli thermosensitive for growth by inactivation of the essential E. coli topoisomerase topo IV, is lethal at all temperatures when PriA, the main replication restart protein, is absent. This lethality is suppressed by the activation of a PriA-independent replication restart pathway (dnaC809 mutation). This result suggests that topo IV acts prior to full-chromosome replication completion.

PMID:: 14762016; [PubMed - indexed for MEDLINE]
PMCID:: PMC344234

Free PMC Article

MeSH Terms, Substances

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Supplemental Content

Save items

Click here to read article using PubReader

Related citations in PubMed

Primosome assembly requirement for replication restart in the Escherichia coli holDG10 replication mutant. [Mol Microbiol. 2002]
Primosome assembly requirement for replication restart in the Escherichia coli holDG10 replication mutant.
Flores MJ, Ehrlich SD, Michel B. Mol Microbiol. 2002 May; 44(3):783-92.
Replication restart in gyrB Escherichia coli mutants. [Mol Microbiol. 2003]
Replication restart in gyrB Escherichia coli mutants.
Grompone G, Ehrlich SD, Michel B. Mol Microbiol. 2003 May; 48(3):845-54.
Requirement for RecFOR-mediated recombination in priA mutant. [Mol Microbiol. 2004]
Requirement for RecFOR-mediated recombination in priA mutant.
Grompone G, Sanchez N, Dusko Ehrlich S, Michel B. Mol Microbiol. 2004 Apr; 52(2):551-62.
Review Filling the gaps in replication restart pathways. [Mol Cell. 2005]
Review Filling the gaps in replication restart pathways.
Lovett ST. Mol Cell. 2005 Mar 18; 17(6):751-2.
Review [Roles of the Holliday intermediate in DNA recombination repair]. [Tanpakushitsu Kakusan Koso. 2001]
Review [Roles of the Holliday intermediate in DNA recombination repair].
Iwasaki H, Shinagawa H. Tanpakushitsu Kakusan Koso. 2001 Jun; 46(8 Suppl):995-1003.

See reviews... See all...

Cited by 5 PubMed Central articles

RNA polymerase mutations that facilitate replication progression in the rep uvrD recF mutant lacking two accessory replicative helicases. [Mol Microbiol. 2010]
RNA polymerase mutations that facilitate replication progression in the rep uvrD recF mutant lacking two accessory replicative helicases.
Baharoglu Z, Lestini R, Duigou S, Michel B. Mol Microbiol. 2010 Jul; 77(2):324-36. Epub 2010 May 19.
Review SSB as an organizer/mobilizer of genome maintenance complexes. [Crit Rev Biochem Mol Biol. 2008]
Review SSB as an organizer/mobilizer of genome maintenance complexes.
Shereda RD, Kozlov AG, Lohman TM, Cox MM, Keck JL. Crit Rev Biochem Mol Biol. 2008 Sep-Oct; 43(5):289-318.
UvrD and UvrD252 counteract RecQ, RecJ, and RecFOR in a rep mutant of Escherichia coli. [J Bacteriol. 2008]
UvrD and UvrD252 counteract RecQ, RecJ, and RecFOR in a rep mutant of Escherichia coli.
Lestini R, Michel B. J Bacteriol. 2008 Sep; 190(17):5995-6001. Epub 2008 Jun 20.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Gene
Gene records that cite the current articles. Citations in Gene are added manually by NCBI or imported from outside public resources.
Gene (GeneRIF)
Gene records that have the current articles as Reference into Function citations (GeneRIFs). NLM staff reviewing the literature while indexing MEDLINE add GeneRIFs manually.
Nucleotide (Weighted)
Nucleotide records associated with the current articles through the Gene database. These are the related sequences on the Gene record that are added manually by NCBI.
Protein (RefSeq)
NCBI protein Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Protein (Weighted)
Protein records associated with the current articles through related Gene database records. These are the related sequences on the Gene record that are added manually by NCBI.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Taxonomy via GenBank
Taxonomy records associated with the current articles through taxonomic information on related molecular database records (Nucleotide, Protein, Gene, SNP, Structure).
GEO Profiles
Gene Expression Omnibus (GEO) Profiles of molecular abundance data. The current articles are references on the Gene record associated with the GEO profile.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

PriA is essential for viability of the Escherichia coli topoisomerase IV parE10(...
PriA is essential for viability of the Escherichia coli topoisomerase IV parE10(Ts) mutant.
J Bacteriol. 2004 Feb ;186(4):1197-9.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: