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Genome Biol. 2004;5(2):206. Epub 2004 Jan 29.

Rewiring the transcriptional regulatory circuits of cells.

Author information

  • 1Department of Genetics, Smurfit Institute, University of Dublin, Trinity College, Dublin 2, Ireland.

Abstract

The molecular mechanisms that regulate gene expression can evolve either by changing the cis-acting DNA elements in promoters, or by replacing the trans-acting regulatory proteins. New data from yeast species show that both processes can happen.

PMID:
14759249
[PubMed - indexed for MEDLINE]
PMCID:
PMC395740
Free PMC Article

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