Format

Send to

Choose Destination
See comment in PubMed Commons below
Orv Hetil. 2003 Nov 30;144(48):2367-70.

[Combined interferon-alfa-2b and ribavirin therapy in patients with recurrent chronic hepatitis c after liver transplantation].

[Article in Hungarian]

Author information

  • 1Semmelweis Egyetem, Altalános Orvostudományi Kar, II. Belklinika, Budapest.

Abstract

Interferon with ribavirin therapy has been proposed for the treatment of hepatitis C recurring in liver transplants.

AIM OF THE STUDY:

Was to assess the efficacy of standard combination therapy (interferon plus ribavirin) of chronic hepatitis C in transplanted patients with recurrent severe HCV induced chronic hepatitis.

METHODS:

12 patients with HCV-PCR positive reaction (genotype 1b) were treated with the therapy of interferon-alpha-2b (3 MU three times a week) and 800-1000 mg ribavirin daily. Liver biopsy had been done in every patients before and after the treatment. Study endpoints were the end of treatment and the 6 month post-therapy sustained virologic response.

RESULTS:

At the end of treatment 3 patients were negative for HCV-PCR and all of them had negative reaction after 6 month follow-up period.

CONCLUSION:

The results are in a good accordance with treatment of patients with chronic hepatitis C without liver transplantation.

PMID:
14753031
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk