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Amino Acids. 2004 Feb;26(1):3-8. Epub 2003 Jul 29.

Metabolism and function in animal tissues of agmatine, a biogenic amine formed from arginine.

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  • 1Dipartimento di Medicina e Oncologia Sperimentale, Sezione di Biochimica, Universit√† di Torino, Torino, Italy.


Recently agmatine, decarboxylated arginine, has been shown to be an important biological compound in several animal tissues. This paper summarizes the known information regarding the transport of arginine, its decarboxylation and the effects of the agmatine formed mainly on NO and polyamine synthesis.

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