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Am J Obstet Gynecol. 2004 Jan;190(1):67-70.

Glassy cell adenocarcinoma of the uterine cervix.

Author information

  • 1Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA. mhopkins@aultman.com

Abstract

OBJECTIVE:

Glassy cell carcinoma of the cervix is a rare variant of cervical cancer accounting for a small percentage of cell types. This study was undertaken to review our experience with glassy cell adenocarcinoma.

STUDY DESIGN:

Review of adenocarcinomas from the period 1970 to 1985 was undertaken. Pathology review and survival analysis was performed comparing the glassy cell adenocarcinomas with other adenocarcinoma cell types.

RESULTS:

Twenty-one patients with glassy cell adenocarcinoma were identified. The mean age was 44 years. The stage distribution showed stage I=10, stage II=8, stage III=1, and stage IV=2. The cumulative survival according to stage was stage I=50%, stage II=36%, stage III=0%, and stage IV=0%. A separate analysis was performed for stage I comparing glassy cell carcinoma with other stage I adenocarcinoma cell types. The survival for stage I nonglassy cell adenocarcinoma was 61% compared with glassy cell adenocarcinoma 48% (n=10) (P=.5). A separate subset for adenosquamous carcinoma alone was performed. The survival for stage I adenosquamous carcinoma (n=30) was 58%. The survival for adenosquamous glassy cell (n=5) was 30% (P=.45).

CONCLUSION:

Glassy cell adenocarcinoma is a small subset of adenocarcinoma. When compared with other adenocarcinomas, survival is not significantly decreased.

PMID:
14749637
[PubMed - indexed for MEDLINE]
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