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Opt Lett. 2004 Jan 15;29(2):171-3.

Real-time measurement of in vitro flow by Fourier-domain color Doppler optical coherence tomography.

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  • 1Department of Medical Physics, University of Vienna, Waehringer Strasse 13, Vienna A-1090, Austria.


The possibility of measuring a full Doppler flow depth profile in parallel by use of frequency-domain optical coherence tomography is demonstrated. The method is based on a local phase analysis of the backscattered signal and allows for imaging of bidirectional Doppler flow. The Doppler frequency limit is 5 kHz for the presented measurements and is set by half of the frame rate of the CCD detector array. We measured the flow of 0.3-microm microspheres suspended in distilled water at controlled flow rates and in vitro human blood flow through a 200-microm capillary with a real-time color-encoded Doppler tomogram rate of 2-3/s.

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