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Curr Biol. 2004 Jan 20;14(2):R70-2.

Cell division: AAAtacking the mitotic spindle.

Author information

  • 1CMM-East, Rm 3071G, Ludwig Institute for Cancer Research, La Jolla, California 92093, USA. icheeseman@ucsd.edu

Abstract

Cell division requires the assembly of a microtubule-based spindle which captures and segregates sister chromatids. But how is this spindle broken down once chromosome segregation is complete? New evidence implicates a highly conserved AAA-ATPase in spindle disassembly at the end of mitosis.

PMID:
14738753
[PubMed - indexed for MEDLINE]
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