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Gynecol Oncol. 1992 Dec;47(3):395-7.

Papillary peritoneal carcinomatosis after prophylactic oophorectomy.

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  • 1Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, Virginia 23507.


Prophylactic oophorectomy has been recommended in patients with a strongly positive family history for ovarian carcinoma. A patient with a strongly positive family history underwent a prophylactic oophorectomy and, 5 years later, developed a primary peritoneal papillary serous adenocarcinoma. A prophylactic oophorectomy does not afford complete protection in some patients with familial ovarian cancer syndrome. Any tissue derived from the coelomic epithelium may potentially undergo multifocal malignant transformation.

[PubMed - indexed for MEDLINE]
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